Here's some thoughts:

1. When you back to town -think about jobs you'd love...okay enjoy.  If you can't work in a cubicle or in high-pressure sales, don't even try.  You'll know if it's a good fit.
2. Don't be afraid to ask an interviewer questions about benefits!  "Tell me about your 401k, health care and insurance."  They want to know if you're committed!
3. Think about future trends- I think energy, health care, baby boomer issues,  and natural resources could be areas to consider.   If you are thinking about a trend- do plenty of research and go for it.
   
4. Don't be afraid to start a business.  It's easier than ever, especially business's that rely on the web.  Sure it's a challenge but it can be a part time venture.